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Source document· February 20, 2026

Merck vs. Bristol Myers: Which Pharma Stock Is a Better Pick in 2026?

View original at finance.yahoo.com
Merck vs. Bristol Myers: Which Pharma Stock Is a Better Pick in 2026? Merck & Co. MRK and Bristol Myers Squibb BMY are major global drugmakers with expansive, diversified portfolios…
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  • Achieved approximately $1 billion in savings in 2025

    80% confidence
  • Operating expenses expected to decline in 2026, supporting margin expansion

    80% confidence
  • Zacks Consensus Estimate for BMY's 2026 EPS suggests increase of 0.33%

    80% confidence
  • Zacks Consensus Estimate for BMY's 2026 sales implies year-over-year decrease of 2.32%

    80% confidence
  • Expects headwind of approximately $2.5 billion from generic competition in 2026

    80% confidence
  • Zacks Consensus Estimate for MRK's 2026 sales implies year-over-year increase of 2.59%

    80% confidence
  • Keytruda targets peak sales of $35 billion by 2028

    80% confidence
  • Phase III pipeline has almost tripled since 2021

    80% confidence
  • Keytruda will lose patient exclusivity in 2028

    80% confidence
  • Annual revenue guidance of $46.0-$47.5 billion for 2026

    80% confidence
  • BMY's relatively attractive valuation and more favorable 2026 outlook position it as the more compelling investment choice versus MRK at present

    80% confidence
  • Zacks Consensus Estimate for MRK's 2026 EPS suggests decline of 38.75%

    80% confidence
  • Legacy Portfolio sales expected to decline 12-16% in 2026

    80% confidence
  • Expects over $70 billion of potential non-risk-adjusted commercial opportunity for the current pipeline by the mid-2030s

    80% confidence
  • Positioned to launch around 20 drugs over the next few years, with many having blockbuster potential

    80% confidence
  • Targeting $2 billion in annualized cost savings by the end of 2027

    80% confidence
What we know · the intelligence behind this page
Live from the substrate
What we're seeing
Biotech Catalyst Wave: Late-2026 Clinical Readouts, PDUFA Dates and Capital Restructuring
A dense cluster of Q4 2026 to Q1 2027 clinical and regulatory catalysts spans hepatitis delta (Vir's ECLIPSE/SOLSTICE), hypertension and sleep apnea (Mineralys' lorundrostat, PDUFA 2026-12-22), severe hypertriglyceridemia (plozasiran), oncology (ivonescimab BLA, PDUFA 2026-11-14) and gene therapy (Krystal). Positive data flow from AASLD and AHA presentations is offset by cost-cutting guidance, milestones slipping into 2027, and a delisting process that signals capital-market stress for some issuers. Near-term value hinges on binary FDA decisions and Phase 3 topline readouts in Q1 2027.
Our read on the data ›
Signals we're tracking
EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
Patterns we're watching ›
Where sources disagree
Ford Motor Company
Both facts give cash for Ford Motor Company at the same point in time (2025-12-31; FY 2025 year-end and Q4 2025 year-end are the same date). Both are labelled USD, but the values are 23,356,000,000 and 23.356, which cannot both be true in USD. The two numbers agree once the second is read as billions (23.356 bn = 23,356,000,000), so the economic content is consistent and the conflict is a unit/scale error in the Q4 2025 record. The period is not the reason for the conflict: a Q4 and an FY figure at the same year-end date should match.
We flag conflicts openly ›
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Merck vs. Bristol Myers: Which Pharma Stock Is a Better Pick in 2026? — Source | Via News | Via News