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Source document· January 25, 2026

How prediction apps like Polymarket are redefining gambling

View original at finance.yahoo.com
How prediction apps like Polymarket are redefining gambling Wanna bet? Throughout history, people have put their money on the uncertain outcomes of all kinds of events…
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  • Prices can become more volatile near elections or big data releases, as these contracts can represent highly volatile events

    80% confidence
  • Prediction markets burst onto the American marketplace in the fall of 2024, and their popularity has only grown since

    80% confidence
  • Prediction market winnings are generally taxed as ordinary income, but some CFTC-regulated platforms like Kalshi may qualify for favorable Section 1256 capital gains treatment, making them potentially more tax-efficient than traditional sports betting

    80% confidence
  • Despite prediction markets being less well-known than traditional polls, platforms like Kalshi and Polymarket proved their worth during the 2024 Presidential Election

    80% confidence
  • Political event contracts are akin to gaming and contrary to the public interest

    80% confidence
  • Media outlets and the public were previously unaware of the accuracy of prediction markets, even though academic research had long supported their effectiveness

    80% confidence
  • While these markets have existed in the U.S. for decades, their use expanded rapidly last year after Kalshi, a federally regulated derivatives exchange and clearinghouse, began offering contracts based on the outcome of political events

    80% confidence
  • Since Kalshi's 2024 legal victory, prediction markets have expanded to offer event contracts based on crypto, climate, economics, financials, companies, and—most controversially—sports

    80% confidence
What we know · the intelligence behind this page
Live from the substrate
What we're seeing
Biotech Catalyst Wave: Late-2026 Clinical Readouts, PDUFA Dates and Capital Restructuring
A dense cluster of Q4 2026 to Q1 2027 clinical and regulatory catalysts spans hepatitis delta (Vir's ECLIPSE/SOLSTICE), hypertension and sleep apnea (Mineralys' lorundrostat, PDUFA 2026-12-22), severe hypertriglyceridemia (plozasiran), oncology (ivonescimab BLA, PDUFA 2026-11-14) and gene therapy (Krystal). Positive data flow from AASLD and AHA presentations is offset by cost-cutting guidance, milestones slipping into 2027, and a delisting process that signals capital-market stress for some issuers. Near-term value hinges on binary FDA decisions and Phase 3 topline readouts in Q1 2027.
Our read on the data ›
Signals we're tracking
EPKINLY Regulatory-Clinical Success Cascade
High probability of expanded label indications, additional combination approvals, and competitive positioning strength in follicular lymphoma market. Predicts positive commercial uptake and potential accelerated review for related indications.
Patterns we're watching ›
Where sources disagree
Ford Motor Company
Both facts give cash for Ford Motor Company at the same point in time (2025-12-31; FY 2025 year-end and Q4 2025 year-end are the same date). Both are labelled USD, but the values are 23,356,000,000 and 23.356, which cannot both be true in USD. The two numbers agree once the second is read as billions (23.356 bn = 23,356,000,000), so the economic content is consistent and the conflict is a unit/scale error in the Q4 2025 record. The period is not the reason for the conflict: a Q4 and an FY figure at the same year-end date should match.
We flag conflicts openly ›
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